General Information of the Compound
| Compound ID |
CP0859348
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| Compound Name |
N-[3-(6-{[(3-Fluorophenyl)methyl]amino}imidazo[1,2-b]pyridazin-3-yl)phenyl]oxane-4-carboxamide
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| Structure |
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| Formula |
C25H24FN5O2
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| Molecular Weight |
445.498
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| Canonical SMILES |
O=C(Nc1ccc(-c2cnc3ccc(NCc4cccc(F)c4)nn23)cc1)C1CCOCC1
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| InChI |
InChI=1S/C25H24FN5O2/c26-20-3-1-2-17(14-20)15-27-23-8-9-24-28-16-22(31(24)30-23)18-4-6-21(7-5-18)29-25(32)19-10-12-33-13-11-19/h1-9,14,16,19H,10-13,15H2,(H,27,30)(H,29,32)
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| InChIKey |
BYKSLICDLDTYLA-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01390, BDNF/NT-3 growth factors receptor
Protein ID: PT00934, High affinity nerve growth factor receptor
Protein ID: PT00936, NT-3 growth factor receptor