General Information of the Compound
| Compound ID |
CP0858321
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| Compound Name |
cilazapril
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| Synonyms |
(1S,9S)-9-(((S)-1-Carboxy-3-phenylpropyl)amino)octahydro-10-oxo-6H-pyridazino(1,2-a)(1,2)diazepine-1-carboxylic acid 9-ethyl estermonohydrate
(4S,7S)-7-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]-6-oxo-1,2,3,4,7,8,9,10-octahydropyridazino[1,2-a]diazepine-4-carboxylic acid
(4S,7S)-7-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]-6-oxo-1,2,3,4,7,8,9,10-octahydropyridazino[1,2-a]diazepine-4-carboxylic acid hydrate
CILAZAPRIL MONOHYDRATE
Cilazapril
Cilazapril (INN)
Cilazapril (USAN)
Cilazapril (anhydrous)
Cilazapril [USAN:INN:BAN:JAN]
Cilazapril anhydrous;Cilazapril hydrate
Cilazapril hydrate (JAN)
Cilazapril, Anhydrous
Cilazaprilum
Cilazaprilum [Latin]
Cilazil
Dynorm
Inhibace
Inhibace (TN)
Inibace
Justor
Ro 31-2848
Ro 31-2848 monohydrate
Ro 34-2848
Ro-31-2848
Ro-312848
Vascace
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| Structure |
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| Formula |
C22H31N3O5
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| Molecular Weight |
417.506
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| Canonical SMILES |
CCOC(=O)[C@H](CCc1ccccc1)N[C@H]1CCCN2CCC[C@@H](C(=O)O)N2C1=O
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| InChI |
InChI=1S/C22H31N3O5/c1-2-30-22(29)18(13-12-16-8-4-3-5-9-16)23-17-10-6-14-24-15-7-11-19(21(27)28)25(24)20(17)26/h3-5,8-9,17-19,23H,2,6-7,10-15H2,1H3,(H,27,28)/t17-,18-,19-/m0/s1
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| InChIKey |
HHHKFGXWKKUNCY-FHWLQOOXSA-N
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| CAS |
88768-40-5
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Clinical Information about the Compound