General Information of the Compound
| Compound ID |
CP0856137
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| Compound Name |
4-(6-{[(2-Methoxyphenyl)methyl]amino}imidazo[1,2-b]pyridazin-3-yl)benzonitrile
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| Structure |
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| Formula |
C21H17N5O
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| Molecular Weight |
355.401
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| Canonical SMILES |
COc1ccccc1CNc1ccc2ncc(-c3ccc(C#N)cc3)n2n1
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| InChI |
InChI=1S/C21H17N5O/c1-27-19-5-3-2-4-17(19)13-23-20-10-11-21-24-14-18(26(21)25-20)16-8-6-15(12-22)7-9-16/h2-11,14H,13H2,1H3,(H,23,25)
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| InChIKey |
IXZOFWVKCDIGGX-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01390, BDNF/NT-3 growth factors receptor
Protein ID: PT00934, High affinity nerve growth factor receptor
Protein ID: PT00936, NT-3 growth factor receptor