General Information of the Compound
Compound ID
CP0828846
Compound Name
SID89856098
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Structure
Formula
C26H24BrClN6O5S2
Molecular Weight
680.006
Canonical SMILES
Br.O=[N+]([O-])c1ccc(N/N=C/c2sc(N3CCOCC3)nc2-c2ccccc2)c(S(=O)(=O)Nc2ccc(Cl)cc2)c1
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InChI
InChI=1S/C26H23ClN6O5S2.BrH/c27-19-6-8-20(9-7-19)31-40(36,37)24-16-21(33(34)35)10-11-22(24)30-28-17-23-25(18-4-2-1-3-5-18)29-26(39-23)32-12-14-38-15-13-32;/h1-11,16-17,30-31H,12-15H2;1H/b28-17+;
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InChIKey
DQWPIKAAAUHCSN-HYEBSWNJSA-N
Physicochemical Property
logP
6.033
Rotatable Bonds
9
Heavy Atom Count
41
Polar Areas
139.06
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
10
Complexity
41

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 16237217
ChEMBL ID
CHEMBL1732967
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT06109, Geminin
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000015 SW480 Homo sapiens (Human)  1
1
Potency ~ 10322.5 nM
   TI
   LI
   LO
   TS
Protein ID: PT06124, Paired box protein Pax-8
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000097 RMG-I Homo sapiens (Human)  1
1
AC50 = 1990 nM
   TI
   LI
   LO
   TS