General Information of the Compound
Compound ID
CP0579558
Compound Name
2-[[(1R)-1-[4-[5-chloro-2-(5-oxo-4H-1,2,4-oxadiazol-3-yl)phenyl]phenyl]ethyl]-(cyclopropylmethyl)amino]-N-ethylsulfonyl-5-methyl-1,3-thiazole-4-carboxamide
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Structure
Formula
C27H28ClN5O5S2
Molecular Weight
602.138
Canonical SMILES
CCS(=O)(=O)NC(=O)c1nc(sc1C)N(CC1CC1)[C@H](C)c1ccc(cc1)-c1cc(Cl)ccc1-c1nc(=O)o[nH]1
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InChI
InChI=1S/C27H28ClN5O5S2/c1-4-40(36,37)32-25(34)23-16(3)39-26(29-23)33(14-17-5-6-17)15(2)18-7-9-19(10-8-18)22-13-20(28)11-12-21(22)24-30-27(35)38-31-24/h7-13,15,17H,4-6,14H2,1-3H3,(H,32,34)(H,30,31,35)/t15-/m1/s1
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InChIKey
MPSZZEIWORIIPB-OAHLLOKOSA-N
Physicochemical Property
logP
5.17232
Rotatable Bonds
10
Heavy Atom Count
40
Polar Areas
138.26
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
9
Complexity
40

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 168280867
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT03813, Chemerin-like receptor 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000681 CAL-1 [Human melanoma] Homo sapiens (Human)  1
1
EC50 = 400 nM
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