General Information of the Compound
Compound ID
CP0571304
Compound Name
5-bromo-2-[2-(pyridin-3-yloxymethyl)piperazin-1-yl]-1,3-benzoxazole;hydrochloride
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Structure
Formula
C17H17BrN4O2
Molecular Weight
389.253
Canonical SMILES
Brc1ccc2oc(nc2c1)N1CCNCC1COc1cccnc1
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InChI
InChI=1S/C17H17BrN4O2.ClH/c18-12-3-4-16-15(8-12)21-17(24-16)22-7-6-20-9-13(22)11-23-14-2-1-5-19-10-14;/h1-5,8,10,13,20H,6-7,9,11H2;1H
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InChIKey
DQNDQNJPABVUOS-UHFFFAOYSA-N
Physicochemical Property
logP
2.8425
Rotatable Bonds
4
Heavy Atom Count
24
Polar Areas
63.42
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
6
Complexity
24

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 90254942
ChEMBL ID
CHEMBL3262128
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02118, Neuronal acetylcholine receptor subunit alpha-7
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000868 PC12 Rattus norvegicus (Rat)  1
1
IC50 = 75 nM
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