General Information of the Compound
| Compound ID |
CP0569702
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| Compound Name |
N-hydroxy-2-(2,3,4,5-tetrafluorophenyl)sulfonyl-3,4-dihydro-1H-isoquinoline-6-carboxamide
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| Structure |
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| Formula |
C16H12F4N2O4S
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| Molecular Weight |
404.341
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| Canonical SMILES |
ONC(=O)c1ccc2CN(CCc2c1)S(=O)(=O)c1cc(F)c(F)c(F)c1F
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| InChI |
InChI=1S/C16H12F4N2O4S/c17-11-6-12(14(19)15(20)13(11)18)27(25,26)22-4-3-8-5-9(16(23)21-24)1-2-10(8)7-22/h1-2,5-6,24H,3-4,7H2,(H,21,23)
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| InChIKey |
YGSMPRINJCSYQS-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02410, Histone deacetylase 11
Protein ID: PT00995, Histone deacetylase 3
Protein ID: PT01213, Histone deacetylase 6
Protein ID: PT01499, Histone deacetylase 8