General Information of the Compound
| Compound ID |
CP0553345
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| Compound Name |
6-[[acetyl-[2-(dimethylamino)ethyl]amino]methyl]-N-[5-cyano-4-(2-methoxyethoxy)pyridin-2-yl]-7-formyl-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide
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| Formula |
C26H33N7O5
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| Molecular Weight |
523.594
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| Canonical SMILES |
COCCOc1cc(NC(=O)N2CCCc3cc(CN(CCN(C)C)C(C)=O)c(C=O)nc23)ncc1C#N
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| InChI |
InChI=1S/C26H33N7O5/c1-18(35)32(9-8-31(2)3)16-20-12-19-6-5-7-33(25(19)29-22(20)17-34)26(36)30-24-13-23(38-11-10-37-4)21(14-27)15-28-24/h12-13,15,17H,5-11,16H2,1-4H3,(H,28,30,36)
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| InChIKey |
IAEBQFAVUQNUCZ-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01343, Fibroblast growth factor receptor 4
Protein ID: PT07029, Fibroblast growth factor receptor 4