Brief Information of the Compound and Protein
Compound Name
6-[[acetyl-[2-(dimethylamino)ethyl]amino]methyl]-N-[5-cyano-4-(2-methoxyethoxy)pyridin-2-yl]-7-formyl-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide
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Canonical SMILES
COCCOc1cc(NC(=O)N2CCCc3cc(CN(CCN(C)C)C(C)=O)c(C=O)nc23)ncc1C#N
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Compound Formula C26H33N7O5
Compound Structure
Protein Name
Fibroblast growth factor receptor 4
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase FGFR family
Uniprot ID
Q03142
Gene Name
FGFR4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  2
1
IC50 = 17 nM
   TI
   LI
   LO
   TS
2
IC50 = 148 nM
   TI
   LI
   LO
   TS