General Information of the Compound
| Compound ID |
CP0544379
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| Compound Name |
N-[5-cyano-4-[3-(dimethylamino)-2,2-dimethylpropoxy]pyridin-2-yl]-6-(difluoromethyl)-7-formyl-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide
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| Structure |
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| Formula |
C24H28F2N6O3
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| Molecular Weight |
486.523
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| Canonical SMILES |
CN(C)CC(C)(C)COc1cc(NC(=O)N2CCCc3cc(C(F)F)c(C=O)nc23)ncc1C#N
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| InChI |
InChI=1S/C24H28F2N6O3/c1-24(2,13-31(3)4)14-35-19-9-20(28-11-16(19)10-27)30-23(34)32-7-5-6-15-8-17(21(25)26)18(12-33)29-22(15)32/h8-9,11-12,21H,5-7,13-14H2,1-4H3,(H,28,30,34)
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| InChIKey |
MADSRQSZSPYHKJ-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01343, Fibroblast growth factor receptor 4
Protein ID: PT07029, Fibroblast growth factor receptor 4