Brief Information of the Compound and Protein
Compound Name
N-[5-cyano-4-[3-(dimethylamino)-2,2-dimethylpropoxy]pyridin-2-yl]-6-(difluoromethyl)-7-formyl-3,4-dihydro-2H-1,8-naphthyridine-1-carboxamide
    Show/Hide
PubChem ID
CID: 118037118
Canonical SMILES
CN(C)CC(C)(C)COc1cc(NC(=O)N2CCCc3cc(C(F)F)c(C=O)nc23)ncc1C#N
    Show/Hide
Compound Formula C24H28F2N6O3
Compound Structure
Protein Name
Fibroblast growth factor receptor 4
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase FGFR family
Uniprot ID
Q03142
Gene Name
FGFR4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  2
1
IC50 = 40 nM
   TI
   LI
   LO
   TS
2
IC50 = 573 nM
   TI
   LI
   LO
   TS