General Information of the Compound
Compound ID
CP0543778
Compound Name
2N-(4-bromobenzyl)-2N-(3-{1-[3-(1H-4-imidazolyl)propylimino]methylthioamino}propyl)-2-pyridinamine
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Structure
Formula
C22H29BrN6S
Molecular Weight
489.487
Canonical SMILES
CS(NCCCN(Cc1ccc(Br)cc1)c1ccccn1)=NCCCc1cnc[nH]1
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InChI
InChI=1S/C22H29BrN6S/c1-30(27-13-4-6-21-16-24-18-26-21)28-14-5-15-29(22-7-2-3-12-25-22)17-19-8-10-20(23)11-9-19/h2-3,7-12,16,18H,4-6,13-15,17H2,1H3,(H,24,26)(H,27,28)
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InChIKey
LIDKVULPNJVWON-UHFFFAOYSA-N
Physicochemical Property
logP
4.533
Rotatable Bonds
12
Heavy Atom Count
30
Polar Areas
69.2
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
4
Complexity
30

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44362068
ChEMBL ID
CHEMBL143100
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01505, Somatostatin receptor type 2
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 4600 nM
   TI
   LI
   LO
   TS
Protein ID: PT01398, Somatostatin receptor type 4
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000051 BHK-21 Mesocricetus auratus (Golden hamster)  1
1
Ki = 50 nM
   TI
   LI
   LO
   TS