General Information of the Compound
| Compound ID |
CP0542792
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| Compound Name |
(2E,4E)-5-(2-ethynyl-1,3-thiazol-4-yl)-N-hydroxypenta-2,4-dienamide
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| Structure |
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| Formula |
C10H8N2O2S
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| Molecular Weight |
220.253
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| Canonical SMILES |
ONC(=O)\C=C\C=C\c1csc(n1)C#C
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| InChI |
InChI=1S/C10H8N2O2S/c1-2-10-11-8(7-15-10)5-3-4-6-9(13)12-14/h1,3-7,14H,(H,12,13)/b5-3+,6-4+
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| InChIKey |
NHXGMOTURBJIGL-GGWOSOGESA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00991, Histone deacetylase 1
Protein ID: PT00995, Histone deacetylase 3
Protein ID: PT00994, Histone deacetylase 4
Protein ID: PT01213, Histone deacetylase 6
Protein ID: PT01499, Histone deacetylase 8