General Information of the Compound
| Compound ID |
CP0538118
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| Compound Name |
8-[4-(2-amino-3-chloropyridin-4-yl)oxy-3-fluoroanilino]-2-(4-fluorophenyl)-3-methyl-2,7-naphthyridin-1-one
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| Structure |
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| Formula |
C26H18ClF2N5O2
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| Molecular Weight |
505.912
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| Canonical SMILES |
Cc1cc2ccnc(Nc3ccc(Oc4ccnc(N)c4Cl)c(F)c3)c2c(=O)n1-c1ccc(F)cc1
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| InChI |
InChI=1S/C26H18ClF2N5O2/c1-14-12-15-8-10-32-25(22(15)26(35)34(14)18-5-2-16(28)3-6-18)33-17-4-7-20(19(29)13-17)36-21-9-11-31-24(30)23(21)27/h2-13H,1H3,(H2,30,31)(H,32,33)
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| InChIKey |
OWJRWSURUBTCKB-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound