Brief Information of the Compound and Protein
Compound Name
8-[4-(2-amino-3-chloropyridin-4-yl)oxy-3-fluoroanilino]-2-(4-fluorophenyl)-3-methyl-2,7-naphthyridin-1-one
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PubChem ID
CID: 71510447
SID: 163499133
Canonical SMILES
Cc1cc2ccnc(Nc3ccc(Oc4ccnc(N)c4Cl)c(F)c3)c2c(=O)n1-c1ccc(F)cc1
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Compound Formula C26H18ClF2N5O2
Compound Structure
Protein Name
Hepatocyte growth factor receptor
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase Met family
Uniprot ID
P08581
Gene Name
MET
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000413 MKN45 Homo sapiens (Human)  1
1
IC50 = 89.8 nM
   TI
   LI
   LO
   TS