General Information of the Compound
| Compound ID |
CP0532047
|
||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Compound Name |
5-phenyl-N-(pyridin-2-ylmethyl)-2-(1,3-thiazol-5-yl)quinazolin-4-amine
Show/Hide
|
||||||||||||||||||
| Structure |
|
||||||||||||||||||
| Formula |
C23H17N5S
|
||||||||||||||||||
| Molecular Weight |
395.491
|
||||||||||||||||||
| Canonical SMILES |
C(Nc1nc(nc2cccc(-c3ccccc3)c12)-c1cncs1)c1ccccn1
Show/Hide
|
||||||||||||||||||
| InChI |
InChI=1S/C23H17N5S/c1-2-7-16(8-3-1)18-10-6-11-19-21(18)23(26-13-17-9-4-5-12-25-17)28-22(27-19)20-14-24-15-29-20/h1-12,14-15H,13H2,(H,26,27,28)
Show/Hide
|
||||||||||||||||||
| InChIKey |
PWBWOYXKXHHDGJ-UHFFFAOYSA-N
|
||||||||||||||||||
| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
|
||||||||||||||||||
| Click to Show/Hide the External Link(s) of This Compound | |||||||||||||||||||
| PubChem ID | |||||||||||||||||||
| ChEMBL ID | |||||||||||||||||||
Map of Molecular Bioactivity Related to the Compound
|
Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
|
|---|
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02768, Potassium voltage-gated channel subfamily A member 5
Protein ID: PT00897, Potassium voltage-gated channel subfamily H member 2