General Information of the Compound
Compound ID
CP0525683
Compound Name
US9447038, 1
    Show/Hide
Structure
Formula
C29H36N2O7
Molecular Weight
524.614
Canonical SMILES
COc1cc(CN(CC(C)C)C(CC(O)=O)c2ccc3OCCc3c2)ccc1OCCN1C(=O)CCC1=O
    Show/Hide
InChI
InChI=1S/C29H36N2O7/c1-19(2)17-30(23(16-29(34)35)21-5-7-24-22(15-21)10-12-37-24)18-20-4-6-25(26(14-20)36-3)38-13-11-31-27(32)8-9-28(31)33/h4-7,14-15,19,23H,8-13,16-18H2,1-3H3,(H,34,35)
    Show/Hide
InChIKey
ZEXUFBYOIYYCJZ-UHFFFAOYSA-N
Physicochemical Property
logP
3.8319
Rotatable Bonds
13
Heavy Atom Count
38
Polar Areas
105.61
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
7
Complexity
38

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 72549346
ChEMBL ID
CHEMBL3907516
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT03433, C-X-C chemokine receptor type 3
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000386 Flp-In-CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 41 nM
   TI
   LI
   LO
   TS