General Information of the Compound
Compound ID
CP0524519
Compound Name
8-butoxy-N-[2-(4-fluorophenyl)ethyl]-7-methoxy-6-nitro-2-oxo-1H-quinoline-3-carboxamide
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Structure
Formula
C23H24FN3O6
Molecular Weight
457.458
Canonical SMILES
CCCCOc1c(OC)c(cc2cc(C(=O)NCCc3ccc(F)cc3)c(=O)[nH]c12)[N+]([O-])=O
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InChI
InChI=1S/C23H24FN3O6/c1-3-4-11-33-21-19-15(13-18(27(30)31)20(21)32-2)12-17(23(29)26-19)22(28)25-10-9-14-5-7-16(24)8-6-14/h5-8,12-13H,3-4,9-11H2,1-2H3,(H,25,28)(H,26,29)
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InChIKey
LIFKXJIIMHZEDS-UHFFFAOYSA-N
Physicochemical Property
logP
3.7354
Rotatable Bonds
10
Heavy Atom Count
33
Polar Areas
123.56
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
6
Complexity
33

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 53494926
SID: 126722697
ChEMBL ID
CHEMBL1822933
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01298, Cannabinoid receptor 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000102 U-87MG ATCC Homo sapiens (Human)  1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS
Protein ID: PT00834, Cannabinoid receptor 2
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000102 U-87MG ATCC Homo sapiens (Human)  1
1
Ki = 1.4 nM
   TI
   LI
   LO
   TS