General Information of the Compound
| Compound ID |
CP0521488
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| Compound Name |
US9266883, 61
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| Structure |
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| Formula |
C20H18F3N5O4
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| Molecular Weight |
449.389
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| Canonical SMILES |
COCCOc1cc(NC(=O)N2CCCc3cc(c(C=O)nc23)C(F)(F)F)ncc1C#N
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| InChI |
InChI=1S/C20H18F3N5O4/c1-31-5-6-32-16-8-17(25-10-13(16)9-24)27-19(30)28-4-2-3-12-7-14(20(21,22)23)15(11-29)26-18(12)28/h7-8,10-11H,2-6H2,1H3,(H,25,27,30)
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| InChIKey |
XNYAZIURZHFKEG-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01343, Fibroblast growth factor receptor 4
Protein ID: PT07029, Fibroblast growth factor receptor 4