Brief Information of the Compound and Protein
Compound Name
US9266883, 61
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PubChem ID
CID: 118036639
Canonical SMILES
COCCOc1cc(NC(=O)N2CCCc3cc(c(C=O)nc23)C(F)(F)F)ncc1C#N
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Compound Formula C20H18F3N5O4
Compound Structure
Protein Name
Fibroblast growth factor receptor 4
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase FGFR family
Uniprot ID
Q03142
Gene Name
FGFR4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  2
1
IC50 = 39 nM
   TI
   LI
   LO
   TS
2
IC50 = 72 nM
   TI
   LI
   LO
   TS