General Information of the Compound
Compound ID
CP0515650
Compound Name
US10167273, Example 9
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Structure
Formula
C19H27N3O3S
Molecular Weight
377.51
Canonical SMILES
CCn1nc(C)c(c1C)S(=O)(=O)N1CCC(CC1)Oc1ccc(C)cc1
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InChI
InChI=1S/C19H27N3O3S/c1-5-22-16(4)19(15(3)20-22)26(23,24)21-12-10-18(11-13-21)25-17-8-6-14(2)7-9-17/h6-9,18H,5,10-13H2,1-4H3
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InChIKey
JWCXZTXNQVBSFE-UHFFFAOYSA-N
Physicochemical Property
logP
3.06036
Rotatable Bonds
5
Heavy Atom Count
26
Polar Areas
64.43
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
5
Complexity
26

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 72548861
ChEMBL ID
CHEMBL3945817
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT04583, Prokineticin receptor 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000278 RBL-2H3 Rattus norvegicus (Rat)  1
1
IC50 = 2300 nM
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