General Information of the Compound
| Compound ID |
CP0510808
|
||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Compound Name |
8-[(2R)-2-hydroxy-2-(4-methyl-1-oxo-3H-2-benzofuran-5-yl)ethyl]-3-(1,2-thiazol-5-yl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one
Show/Hide
|
||||||||||||||||||
| Structure |
|
||||||||||||||||||
| Formula |
C21H23N3O5S
|
||||||||||||||||||
| Molecular Weight |
429.498
|
||||||||||||||||||
| Canonical SMILES |
Cc1c2COC(=O)c2ccc1[C@@H](O)CN1CCC2(CN(C(=O)O2)c2ccns2)CC1
Show/Hide
|
||||||||||||||||||
| InChI |
InChI=1S/C21H23N3O5S/c1-13-14(2-3-15-16(13)11-28-19(15)26)17(25)10-23-8-5-21(6-9-23)12-24(20(27)29-21)18-4-7-22-30-18/h2-4,7,17,25H,5-6,8-12H2,1H3/t17-/m0/s1
Show/Hide
|
||||||||||||||||||
| InChIKey |
AXGWMCUXLYZWRM-KRWDZBQOSA-N
|
||||||||||||||||||
| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
|
||||||||||||||||||
| Click to Show/Hide the External Link(s) of This Compound | |||||||||||||||||||
| PubChem ID | |||||||||||||||||||
| ChEMBL ID | |||||||||||||||||||
Map of Molecular Bioactivity Related to the Compound
|
Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
|
|---|
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT03667, ATP-sensitive inward rectifier potassium channel 1
Protein ID: PT00897, Potassium voltage-gated channel subfamily H member 2