General Information of the Compound
| Compound ID |
CP0494134
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| Compound Name |
1-[4-[7-(dimethylamino)quinazolin-4-yl]oxyphenyl]-3-(4-methoxyphenyl)urea
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| Structure |
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| Formula |
C24H23N5O3
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| Molecular Weight |
429.48
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| Canonical SMILES |
COc1ccc(NC(=O)Nc2ccc(Oc3ncnc4cc(ccc34)N(C)C)cc2)cc1
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| InChI |
InChI=1S/C24H23N5O3/c1-29(2)18-8-13-21-22(14-18)25-15-26-23(21)32-20-11-6-17(7-12-20)28-24(30)27-16-4-9-19(31-3)10-5-16/h4-15H,1-3H3,(H2,27,28,30)
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| InChIKey |
RTWJZWFAMFOLDK-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00980, Aurora kinase A
Protein ID: PT01223, Aurora kinase B
Protein ID: PT01008, Macrophage colony-stimulating factor 1 receptor