General Information of the Compound
| Compound ID |
CP0490075
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| Compound Name |
US9238644, 4
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| Structure |
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| Formula |
C26H26F3N5O
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| Molecular Weight |
481.522
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| Canonical SMILES |
NC(=O)C1(CC1)c1ccccc1CCc1nc(Nc2ccc(cc2)C2CNC2)ncc1C(F)(F)F
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| InChI |
InChI=1S/C26H26F3N5O/c27-26(28,29)21-15-32-24(33-19-8-5-16(6-9-19)18-13-31-14-18)34-22(21)10-7-17-3-1-2-4-20(17)25(11-12-25)23(30)35/h1-6,8-9,15,18,31H,7,10-14H2,(H2,30,35)(H,32,33,34)
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| InChIKey |
QXWHXZVEZDYDHA-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00864, Vascular endothelial growth factor receptor 2
Protein ID: PT00925, Vascular endothelial growth factor receptor 3