Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US9238644, 4
    Show/Hide
 PubChem ID
CID: 73296427
Canonical SMILES
NC(=O)C1(CC1)c1ccccc1CCc1nc(Nc2ccc(cc2)C2CNC2)ncc1C(F)(F)F
    Show/Hide
Compound Formula C26H26F3N5O
Compound Structure
Protein Name
 Protein Info 
Vascular endothelial growth factor receptor 3
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase VEGFR family
Uniprot ID
P35916
Gene Name
FLT4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000749 HUVEC-C
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 38 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 22 nM