General Information of the Compound
Compound ID
CP0488654
Compound Name
5-(4-methoxy-3-phenylmethoxyphenyl)-2,4,4-trimethylpyrazol-3-one
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Structure
Formula
C20H22N2O3
Molecular Weight
338.407
Canonical SMILES
COc1ccc(cc1OCc1ccccc1)C1=NN(C)C(=O)C1(C)C
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InChI
InChI=1S/C20H22N2O3/c1-20(2)18(21-22(3)19(20)23)15-10-11-16(24-4)17(12-15)25-13-14-8-6-5-7-9-14/h5-12H,13H2,1-4H3
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InChIKey
MVRJRQHDILNPDQ-UHFFFAOYSA-N
Physicochemical Property
logP
3.4765
Rotatable Bonds
5
Heavy Atom Count
25
Polar Areas
51.13
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
4
Complexity
25

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 71458910
SID: 163455484
ChEMBL ID
CHEMBL2171662
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00212, Phosphodiesterase
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 10000 nM
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