General Information of the Compound
| Compound ID |
CP0487146
|
||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Compound Name |
N-(3,3-difluorocyclobutyl)-1-methyl-6-(1H-pyrazolo[4,3-b]pyridin-3-ylamino)indazole-3-carboxamide
Show/Hide
|
||||||||||||||||||
| Structure |
|
||||||||||||||||||
| Formula |
C19H17F2N7O
|
||||||||||||||||||
| Molecular Weight |
397.389
|
||||||||||||||||||
| Canonical SMILES |
Cn1nc(C(=O)NC2CC(F)(F)C2)c2ccc(Nc3n[nH]c4cccnc34)cc12
Show/Hide
|
||||||||||||||||||
| InChI |
InChI=1S/C19H17F2N7O/c1-28-14-7-10(23-17-16-13(25-26-17)3-2-6-22-16)4-5-12(14)15(27-28)18(29)24-11-8-19(20,21)9-11/h2-7,11H,8-9H2,1H3,(H,24,29)(H2,23,25,26)
Show/Hide
|
||||||||||||||||||
| InChIKey |
CWVGBFDKAQZNFM-UHFFFAOYSA-N
|
||||||||||||||||||
| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
|
||||||||||||||||||
| Click to Show/Hide the External Link(s) of This Compound | |||||||||||||||||||
| PubChem ID | |||||||||||||||||||
| ChEMBL ID | |||||||||||||||||||
Map of Molecular Bioactivity Related to the Compound
|
Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
|
|---|
Table of Molecular Bioactivities Related to the Compound