General Information of the Compound
| Compound ID |
CP0482293
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| Compound Name |
3-[5-cyano-4-(2-methoxyethylamino)pyridin-2-yl]-1-(6-formylpyridin-2-yl)-1-methylurea
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| Structure |
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| Formula |
C17H18N6O3
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| Molecular Weight |
354.37
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| Canonical SMILES |
COCCNc1cc(NC(=O)N(C)c2cccc(C=O)n2)ncc1C#N
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| InChI |
InChI=1S/C17H18N6O3/c1-23(16-5-3-4-13(11-24)21-16)17(25)22-15-8-14(19-6-7-26-2)12(9-18)10-20-15/h3-5,8,10-11H,6-7H2,1-2H3,(H2,19,20,22,25)
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| InChIKey |
LLKJNWLQWOLODU-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01343, Fibroblast growth factor receptor 4
Protein ID: PT07029, Fibroblast growth factor receptor 4
Cell Viability or Cytotoxicity Assay
| Cell Line ID | Cell Line Name | Cell Line Organism | |
| CL000148 | Huh-7 | Homo sapiens (Human) | 1 |
| 1 |
IC50 > 3000 nM
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