General Information of the Compound
| Compound ID |
CP0478201
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| Compound Name |
US9186360, 34
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| Structure |
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| Formula |
C20H16F3N5O4S
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| Molecular Weight |
479.44
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| Canonical SMILES |
Cn1c2ccn(CC(=O)Nc3nc(cs3)-c3ccc(OC(F)(F)F)cc3)c2c(=O)n(C)c1=O
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| InChI |
InChI=1S/C20H16F3N5O4S/c1-26-14-7-8-28(16(14)17(30)27(2)19(26)31)9-15(29)25-18-24-13(10-33-18)11-3-5-12(6-4-11)32-20(21,22)23/h3-8,10H,9H2,1-2H3,(H,24,25,29)
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| InChIKey |
MQBRPGZLHZUVDU-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02149, Transient receptor potential cation channel subfamily A member 1
Protein ID: PT03065, Transient receptor potential cation channel subfamily M member 8
Protein ID: PT02183, Transient receptor potential cation channel subfamily V member 1
Protein ID: PT04494, Transient receptor potential cation channel subfamily V member 3
Protein ID: PT03081, Transient receptor potential cation channel subfamily V member 4