General Information of the Compound
Compound ID
CP0477924
Compound Name
N-[2-(azepan-1-yl)ethyl]-8-methyl-4-oxo-5H-thieno[3,2-c]quinoline-2-carboxamide
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Structure
Formula
C21H25N3O2S
Molecular Weight
383.517
Canonical SMILES
Cc1ccc2[nH]c(=O)c3cc(sc3c2c1)C(=O)NCCN1CCCCCC1
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InChI
InChI=1S/C21H25N3O2S/c1-14-6-7-17-15(12-14)19-16(20(25)23-17)13-18(27-19)21(26)22-8-11-24-9-4-2-3-5-10-24/h6-7,12-13H,2-5,8-11H2,1H3,(H,22,26)(H,23,25)
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InChIKey
WJKSRLPDBCLPGP-UHFFFAOYSA-N
Physicochemical Property
logP
3.65702
Rotatable Bonds
4
Heavy Atom Count
27
Polar Areas
65.2
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
4
Complexity
27

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 20879988
ChEMBL ID
CHEMBL2381220
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT04108, Atypical chemokine receptor 3
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 7000 nM
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