General Information of the Compound
Compound ID
CP0471787
Compound Name
2-chloro-5,8-dimethoxy-3-piperidin-1-ylnaphthalene-1,4-dione
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Structure
Formula
C17H18ClNO4
Molecular Weight
335.787
Canonical SMILES
COc1ccc(OC)c2C(=O)C(N3CCCCC3)=C(Cl)C(=O)c12
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InChI
InChI=1S/C17H18ClNO4/c1-22-10-6-7-11(23-2)13-12(10)16(20)14(18)15(17(13)21)19-8-4-3-5-9-19/h6-7H,3-5,8-9H2,1-2H3
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InChIKey
VNEXOZRHKKBKEC-UHFFFAOYSA-N
Physicochemical Property
logP
3.0191
Rotatable Bonds
3
Heavy Atom Count
23
Polar Areas
55.84
Hydrogen Bond Donor Count
0
Hydrogen Bond Acceptor Count
5
Complexity
23

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 155522092
ChEMBL ID
CHEMBL4452005
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT05453, G-protein coupled receptor 55
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000111 MDA-MB-231 Homo sapiens (Human)  1
1
EC50 > 10000 nM
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   LI
   LO
   TS