General Information of the Compound
Compound ID
CP0471586
Compound Name
Methyl 2-(4-Chlorophenyl)-2-(1-((3,5-dimethyl-1H-pyrazol-4-yl) sulfonyl)piperidin-4-ylidene)acetate
    Show/Hide
Structure
Formula
C19H22ClN3O4S
Molecular Weight
423.922
Canonical SMILES
COC(=O)C(=C1CCN(CC1)S(=O)(=O)c1c(C)n[nH]c1C)c1ccc(Cl)cc1
    Show/Hide
InChI
InChI=1S/C19H22ClN3O4S/c1-12-18(13(2)22-21-12)28(25,26)23-10-8-15(9-11-23)17(19(24)27-3)14-4-6-16(20)7-5-14/h4-7H,8-11H2,1-3H3,(H,21,22)
    Show/Hide
InChIKey
AJJRKLYODDLARY-UHFFFAOYSA-N
Physicochemical Property
logP
3.09124
Rotatable Bonds
4
Heavy Atom Count
28
Polar Areas
92.36
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
5
Complexity
28

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 86580540
ChEMBL ID
CHEMBL3941024
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT04583, Prokineticin receptor 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000278 RBL-2H3 Rattus norvegicus (Rat)  1
1
IC50 = 3100 nM
   TI
   LI
   LO
   TS