General Information of the Compound
| Compound ID |
CP0470781
|
||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Compound Name |
N-hydroxy-4-[[3-[2-(4-hydroxyphenyl)ethyl]-2,4-dioxoquinazolin-1-yl]methyl]benzamide
Show/Hide
|
||||||||||||||||||
| Structure |
|
||||||||||||||||||
| Formula |
C24H21N3O5
|
||||||||||||||||||
| Molecular Weight |
431.448
|
||||||||||||||||||
| Canonical SMILES |
ONC(=O)c1ccc(Cn2c3ccccc3c(=O)n(CCc3ccc(O)cc3)c2=O)cc1
Show/Hide
|
||||||||||||||||||
| InChI |
InChI=1S/C24H21N3O5/c28-19-11-7-16(8-12-19)13-14-26-23(30)20-3-1-2-4-21(20)27(24(26)31)15-17-5-9-18(10-6-17)22(29)25-32/h1-12,28,32H,13-15H2,(H,25,29)
Show/Hide
|
||||||||||||||||||
| InChIKey |
PWUOLJLDIZJJPB-UHFFFAOYSA-N
|
||||||||||||||||||
| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
|
||||||||||||||||||
| Click to Show/Hide the External Link(s) of This Compound | |||||||||||||||||||
| PubChem ID | |||||||||||||||||||
| ChEMBL ID | |||||||||||||||||||
Map of Molecular Bioactivity Related to the Compound
|
Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
|
|---|
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00991, Histone deacetylase 1
Protein ID: PT02410, Histone deacetylase 11
Protein ID: PT01213, Histone deacetylase 6
Protein ID: PT01499, Histone deacetylase 8