General Information of the Compound
| Compound ID |
CP0449764
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| Compound Name |
2-cyclobutyl-6,7-dimethoxy-4-(4-phenylpiperazin-1-yl)quinazoline
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| Structure |
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| Formula |
C24H28N4O2
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| Molecular Weight |
404.514
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| Canonical SMILES |
COc1cc2nc(nc(N3CCN(CC3)c3ccccc3)c2cc1OC)C1CCC1
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| InChI |
InChI=1S/C24H28N4O2/c1-29-21-15-19-20(16-22(21)30-2)25-23(17-7-6-8-17)26-24(19)28-13-11-27(12-14-28)18-9-4-3-5-10-18/h3-5,9-10,15-17H,6-8,11-14H2,1-2H3
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| InChIKey |
RABPYCTZPIOHBV-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT03308, G-protein coupled receptor 35
Protein ID: PT02429, Neurotensin receptor type 1
Protein ID: PT02626, Neurotensin receptor type 2