General Information of the Compound
Compound ID
CP0448534
Compound Name
3-O-Methyldopamine hydrochloride
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Synonyms
3-methoxy-4-hydroxyphenethylamine
3-methoxytyramine
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Structure
Formula
C9H13NO2
Molecular Weight
167.208
Canonical SMILES
COc1cc(CCN)ccc1O
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InChI
InChI=1S/C9H13NO2/c1-12-9-6-7(4-5-10)2-3-8(9)11/h2-3,6,11H,4-5,10H2,1H3
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InChIKey
DIVQKHQLANKJQO-UHFFFAOYSA-N
Physicochemical Property
logP
0.902
Rotatable Bonds
3
Heavy Atom Count
12
Polar Areas
55.48
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
3
Complexity
12

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 1669
SID: 15147119
ChEMBL ID
CHEMBL1160785
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00957, D(2) dopamine receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000049 C6 Rattus norvegicus (Rat)  1
1
Kd = 94000 nM
   TI
   LI
   LO
   TS
Protein ID: PT04763, Trace amine-associated receptor 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
EC50 = 308 nM
   TI
   LI
   LO
   TS
Clinical Information about the Compound
Drug 1 ( 3-methoxytyramine )
Drug Name 3-methoxytyramine