General Information of the Compound
| Compound ID |
CP0443901
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| Compound Name |
Aminoclonidine, p
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| Synonyms |
2,6-dichloro-1-N-(4,5-dihydro-1H-imidazol-2-yl)benzene-1,4-diamine
2,6-dichloro-N(1)-(4,5-dihydro-1H-imidazol-2-yl)benzene-1,4-diamine
2-(4-Amino-2,6-dichloroanilino)-2-imidazoline hydrochloride
2-(4-amino-2,6-dichloro)phenyliminoimidazolidine
4-Aminoclonidine
ALO 2145
Aplonidine
Apraclonidina
Apraclonidina [INN-Spanish]
Apraclonidine
Apraclonidine (INN)
Apraclonidine [INN:BAN]
Apraclonidinum
Apraclonidinum [INN-Latin]
Iopidine
Iopidine (TN)
Iopidine Eye
P-aminoclonidine
Para-aminoclonidine
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| Structure |
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| Formula |
C9H10Cl2N4
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| Molecular Weight |
245.113
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| Canonical SMILES |
Nc1cc(Cl)c(NC2=NCCN2)c(Cl)c1
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| InChI |
InChI=1S/C9H10Cl2N4/c10-6-3-5(12)4-7(11)8(6)15-9-13-1-2-14-9/h3-4H,1-2,12H2,(H2,13,14,15)
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| InChIKey |
IEJXVRYNEISIKR-UHFFFAOYSA-N
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| CAS |
66711-21-5
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01650, Alpha-2A adrenergic receptor
Protein ID: PT03109, Alpha-2B adrenergic receptor
Protein ID: PT01598, Alpha-2C adrenergic receptor
Clinical Information about the Compound