General Information of the Compound
Compound ID
CP0436541
Compound Name
N-(5-aminopentyl)-4-(1H-indol-3-yl)-N-(3-phenylpropyl)butanamide
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Structure
Formula
C26H35N3O
Molecular Weight
405.586
Canonical SMILES
NCCCCCN(CCCc1ccccc1)C(=O)CCCc1c[nH]c2ccccc12
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InChI
InChI=1S/C26H35N3O/c27-18-7-2-8-19-29(20-10-13-22-11-3-1-4-12-22)26(30)17-9-14-23-21-28-25-16-6-5-15-24(23)25/h1,3-6,11-12,15-16,21,28H,2,7-10,13-14,17-20,27H2
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InChIKey
CFZBOPYQAMXMKM-UHFFFAOYSA-N
Physicochemical Property
logP
5.081
Rotatable Bonds
13
Heavy Atom Count
30
Polar Areas
62.12
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
2
Complexity
30

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 44434639
ChEMBL ID
CHEMBL393557
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01325, Melanocortin receptor 3
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
Ki = 61000 nM
   TI
   LI
   LO
   TS
Protein ID: PT01804, Melanocortin receptor 5
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
Ki = 19000 nM
   TI
   LI
   LO
   TS
Protein ID: PT01440, Melanocyte-stimulating hormone receptor
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000087 B16 Mus musculus (Mouse)  1
1
Ki = 18000 nM
   TI
   LI
   LO
   TS