General Information of the Compound
| Compound ID |
CP0436003
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| Compound Name |
1-(3-(6,7- dimethoxy- quinazolin- 4- ylthio)phenyl)- 3- (3-(2- fluoropropan-2- yl)isoxazol-5-yl) urea
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| Structure |
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| Formula |
C23H22FN5O4S
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| Molecular Weight |
483.525
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| Canonical SMILES |
COc1cc2ncnc(Sc3cccc(NC(=O)Nc4cc(no4)C(C)(C)F)c3)c2cc1OC
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| InChI |
InChI=1S/C23H22FN5O4S/c1-23(2,24)19-11-20(33-29-19)28-22(30)27-13-6-5-7-14(8-13)34-21-15-9-17(31-3)18(32-4)10-16(15)25-12-26-21/h5-12H,1-4H3,(H2,27,28,30)
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| InChIKey |
UCNNCXUHEWXYRD-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound