General Information of the Compound
| Compound ID |
CP0426160
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| Compound Name |
N-[5-[3-(3-hydroxypyrrolidin-1-yl)-6-[2-methoxy-4-(4-methylpiperazin-1-yl)anilino]pyridin-2-yl]oxy-2-methylphenyl]prop-2-enamide
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| Structure |
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| Formula |
C31H38N6O4
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| Molecular Weight |
558.683
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| Canonical SMILES |
COc1cc(ccc1Nc1ccc(N2CCC(O)C2)c(Oc2ccc(C)c(NC(=O)C=C)c2)n1)N1CCN(C)CC1
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| InChI |
InChI=1S/C31H38N6O4/c1-5-30(39)33-26-19-24(8-6-21(26)2)41-31-27(37-13-12-23(38)20-37)10-11-29(34-31)32-25-9-7-22(18-28(25)40-4)36-16-14-35(3)15-17-36/h5-11,18-19,23,38H,1,12-17,20H2,2-4H3,(H,32,34)(H,33,39)
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| InChIKey |
PONPXMDPXUKJAO-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound