General Information of the Compound
| Compound ID |
CP0424218
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| Compound Name |
4-[[3-[2-(3-fluorophenyl)ethyl]-2,4-dioxoquinazolin-1-yl]methyl]-N-hydroxybenzamide
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| Structure |
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| Formula |
C24H20FN3O4
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| Molecular Weight |
433.439
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| Canonical SMILES |
ONC(=O)c1ccc(Cn2c3ccccc3c(=O)n(CCc3cccc(F)c3)c2=O)cc1
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| InChI |
InChI=1S/C24H20FN3O4/c25-19-5-3-4-16(14-19)12-13-27-23(30)20-6-1-2-7-21(20)28(24(27)31)15-17-8-10-18(11-9-17)22(29)26-32/h1-11,14,32H,12-13,15H2,(H,26,29)
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| InChIKey |
YPSQQRVXHGHJKA-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00991, Histone deacetylase 1
Protein ID: PT02410, Histone deacetylase 11
Protein ID: PT01213, Histone deacetylase 6
Protein ID: PT01499, Histone deacetylase 8