General Information of the Compound
| Compound ID |
CP0424216
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| Compound Name |
4-[[7-cyclopropyl-2,4-dioxo-3-(2-phenylethyl)quinazolin-1-yl]methyl]-N-hydroxybenzamide
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| Structure |
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| Formula |
C27H25N3O4
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| Molecular Weight |
455.514
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| Canonical SMILES |
ONC(=O)c1ccc(Cn2c3cc(ccc3c(=O)n(CCc3ccccc3)c2=O)C2CC2)cc1
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| InChI |
InChI=1S/C27H25N3O4/c31-25(28-34)21-8-6-19(7-9-21)17-30-24-16-22(20-10-11-20)12-13-23(24)26(32)29(27(30)33)15-14-18-4-2-1-3-5-18/h1-9,12-13,16,20,34H,10-11,14-15,17H2,(H,28,31)
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| InChIKey |
GLZCWMXIUBFQEM-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00991, Histone deacetylase 1
Protein ID: PT02410, Histone deacetylase 11
Protein ID: PT01213, Histone deacetylase 6
Protein ID: PT01499, Histone deacetylase 8