General Information of the Compound
Compound ID
CP0418801
Compound Name
1-{2-[(5-Bromo-pyridin-2-yl)-(3,4-dichloro-benzyl)-amino]-ethyl}-3-(3-dimethylamino-propyl)-thiourea
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Structure
Formula
C20H26BrCl2N5S
Molecular Weight
519.34
Canonical SMILES
CN(C)CCCNC(=S)NCCN(Cc1ccc(Cl)c(Cl)c1)c1ccc(Br)cn1
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InChI
InChI=1S/C20H26BrCl2N5S/c1-27(2)10-3-8-24-20(29)25-9-11-28(19-7-5-16(21)13-26-19)14-15-4-6-17(22)18(23)12-15/h4-7,12-13H,3,8-11,14H2,1-2H3,(H2,24,25,29)
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InChIKey
HKMFVCXUMMRKOQ-UHFFFAOYSA-N
Physicochemical Property
logP
4.5733
Rotatable Bonds
10
Heavy Atom Count
29
Polar Areas
43.43
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
4
Complexity
29

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 10768264
SID: 15805836
ChEMBL ID
CHEMBL143164
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01505, Somatostatin receptor type 2
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 2000 nM
   TI
   LI
   LO
   TS
Protein ID: PT01398, Somatostatin receptor type 4
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000051 BHK-21 Mesocricetus auratus (Golden hamster)  1
1
Ki = 803 nM
   TI
   LI
   LO
   TS