General Information of the Compound
Compound ID
CP0415931
Compound Name
(4-chlorophenyl)-[2-(pyridin-3-yloxymethyl)piperazin-1-yl]methanone;hydrochloride
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Structure
Formula
C17H18ClN3O2
Molecular Weight
331.803
Canonical SMILES
Clc1ccc(cc1)C(=O)N1CCNCC1COc1cccnc1
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InChI
InChI=1S/C17H18ClN3O2.ClH/c18-14-5-3-13(4-6-14)17(22)21-9-8-20-10-15(21)12-23-16-2-1-7-19-11-16;/h1-7,11,15,20H,8-10,12H2;1H
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InChIKey
SGQFZOFXPFNTEQ-UHFFFAOYSA-N
Physicochemical Property
logP
2.228
Rotatable Bonds
4
Heavy Atom Count
23
Polar Areas
54.46
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
4
Complexity
23

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 90643556
ChEMBL ID
CHEMBL3262148
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02118, Neuronal acetylcholine receptor subunit alpha-7
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000868 PC12 Rattus norvegicus (Rat)  1
1
IC50 = 6100 nM
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