General Information of the Compound
Compound ID
CP0413964
Compound Name
2-ethoxy-4-[5-[[[(2R)-2-[(1R)-1-[formyl(hydroxy)amino]propyl]heptanoyl]amino]methylcarbamoyl]furan-2-yl]benzoic acid
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Structure
Formula
C26H35N3O8
Molecular Weight
517.579
Canonical SMILES
CCCCC[C@H]([C@@H](CC)N(O)C=O)C(=O)NCNC(=O)c1ccc(o1)-c1ccc(C(O)=O)c(OCC)c1
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InChI
InChI=1S/C26H35N3O8/c1-4-7-8-9-18(20(5-2)29(35)16-30)24(31)27-15-28-25(32)22-13-12-21(37-22)17-10-11-19(26(33)34)23(14-17)36-6-3/h10-14,16,18,20,35H,4-9,15H2,1-3H3,(H,27,31)(H,28,32)(H,33,34)/t18-,20-/m1/s1
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InChIKey
HHBDPCCWQBHZLA-UYAOXDASSA-N
Physicochemical Property
logP
3.6697
Rotatable Bonds
16
Heavy Atom Count
37
Polar Areas
158.41
Hydrogen Bond Donor Count
4
Hydrogen Bond Acceptor Count
7
Complexity
37

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 91824149
ChEMBL ID
CHEMBL4209125
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01896, Bone morphogenetic protein 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 < 1 nM
   TI
   LI
   LO
   TS
Protein ID: PT04609, Tolloid-like protein 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000856 CHO E1a Cricetulus griseus (Chinese hamster)  1
1
IC50 < 398.11 nM
   TI
   LI
   LO
   TS
Protein ID: PT06770, Tolloid-like protein 2
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000856 CHO E1a Cricetulus griseus (Chinese hamster)  1
1
IC50 < 794.33 nM
   TI
   LI
   LO
   TS