General Information of the Compound
Compound ID
CP0410449
Compound Name
2-[[2-(5-quinolin-3-ylindol-1-yl)acetyl]amino]acetic acid
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Structure
Formula
C21H17N3O3
Molecular Weight
359.385
Canonical SMILES
OC(=O)CNC(=O)Cn1ccc2cc(ccc12)-c1cnc2ccccc2c1
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InChI
InChI=1S/C21H17N3O3/c25-20(23-12-21(26)27)13-24-8-7-16-9-14(5-6-19(16)24)17-10-15-3-1-2-4-18(15)22-11-17/h1-11H,12-13H2,(H,23,25)(H,26,27)
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InChIKey
ISALHTCQJORZRQ-UHFFFAOYSA-N
Physicochemical Property
logP
3.0573
Rotatable Bonds
5
Heavy Atom Count
27
Polar Areas
84.22
Hydrogen Bond Donor Count
2
Hydrogen Bond Acceptor Count
4
Complexity
27

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 118708045
ChEMBL ID
CHEMBL3315210
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02429, Neurotensin receptor type 1
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
EC50 > 100000 nM
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