General Information of the Compound
| Compound ID |
CP0408075
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| Compound Name |
2-[2-(4-fluorophenyl)imidazo[1,2-a]pyrimidin-7-yl]-5,8-dimethyl-[1,2,4]triazolo[1,5-a]pyrazine
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| Structure |
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| Formula |
C19H14FN7
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| Molecular Weight |
359.368
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| Canonical SMILES |
Cc1ncc(C)n2nc(nc12)-c1ccn2cc(nc2n1)-c1ccc(F)cc1
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| InChI |
InChI=1S/C19H14FN7/c1-11-9-21-12(2)18-24-17(25-27(11)18)15-7-8-26-10-16(23-19(26)22-15)13-3-5-14(20)6-4-13/h3-10H,1-2H3
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| InChIKey |
STHVTZBYGXURQK-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01875, cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Protein ID: PT02038, Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C
Protein ID: PT03075, High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A