General Information of the Compound
| Compound ID |
CP0408052
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| Compound Name |
5-[4-(dimethylamino)phenyl]-N-(pyridin-2-ylmethyl)-2-pyrimidin-5-ylquinazolin-4-amine
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| Structure |
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| Formula |
C26H23N7
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| Molecular Weight |
433.519
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| Canonical SMILES |
CN(C)c1ccc(cc1)-c1cccc2nc(nc(NCc3ccccn3)c12)-c1cncnc1
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| InChI |
InChI=1S/C26H23N7/c1-33(2)21-11-9-18(10-12-21)22-7-5-8-23-24(22)26(30-16-20-6-3-4-13-29-20)32-25(31-23)19-14-27-17-28-15-19/h3-15,17H,16H2,1-2H3,(H,30,31,32)
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| InChIKey |
RCYQMCZETBLKND-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02768, Potassium voltage-gated channel subfamily A member 5
Protein ID: PT00897, Potassium voltage-gated channel subfamily H member 2