General Information of the Compound
Compound ID
CP0399809
Compound Name
2-Hexadecanoylamino-3-(4-phosphonooxy-phenyl)-propionic acid
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Structure
Formula
C25H42NO7P
Molecular Weight
499.585
Canonical SMILES
CCCCCCCCCCCCCCCC(=O)N[C@@H](Cc1ccc(OP(O)(O)=O)cc1)C(O)=O
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InChI
InChI=1S/C25H42NO7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-24(27)26-23(25(28)29)20-21-16-18-22(19-17-21)33-34(30,31)32/h16-19,23H,2-15,20H2,1H3,(H,26,27)(H,28,29)(H2,30,31,32)/t23-/m0/s1
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InChIKey
XUJHGZCBICJAJS-QHCPKHFHSA-N
Physicochemical Property
logP
5.7513
Rotatable Bonds
20
Heavy Atom Count
34
Polar Areas
133.16
Hydrogen Bond Donor Count
4
Hydrogen Bond Acceptor Count
4
Complexity
34

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 11755685
SID: 16863450
ChEMBL ID
CHEMBL189515
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT04536, Lysophosphatidic acid receptor 2
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000466 McA-RH7777 Rattus norvegicus (Rat)  1
1
EC50 ~ 11000 nM
   TI
   LI
   LO
   TS
Protein ID: PT02824, Lysophosphatidic acid receptor 3
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000466 McA-RH7777 Rattus norvegicus (Rat)  2
1
IC50 = 5570 nM
   TI
   LI
   LO
   TS
2
Ki = 2325 nM
   TI
   LI
   LO
   TS