General Information of the Compound
Compound ID
CP0389305
Compound Name
N-[(3-fluoro-4-methoxyphenyl)methyl]-2,4-dimethylquinoline-6-carboxamide
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Structure
Formula
C20H19FN2O2
Molecular Weight
338.382
Canonical SMILES
COc1ccc(CNC(=O)c2ccc3nc(C)cc(C)c3c2)cc1F
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InChI
InChI=1S/C20H19FN2O2/c1-12-8-13(2)23-18-6-5-15(10-16(12)18)20(24)22-11-14-4-7-19(25-3)17(21)9-14/h4-10H,11H2,1-3H3,(H,22,24)
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InChIKey
PMRJVLFDFOIIDK-UHFFFAOYSA-N
Physicochemical Property
logP
3.92934
Rotatable Bonds
4
Heavy Atom Count
25
Polar Areas
51.22
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
3
Complexity
25

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 135126272
ChEMBL ID
CHEMBL4216322
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01736, Muscarinic acetylcholine receptor M4
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
EC50 > 10000 nM
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