General Information of the Compound
Compound ID
CP0322301
Compound Name
N-[3-[[4-[4-(piperidine-1-carbonyl)anilino]-1,3,5-triazin-2-yl]amino]phenyl]prop-2-enamide
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Formula
C24H25N7O2
Molecular Weight
443.511
Canonical SMILES
C=CC(=O)Nc1cccc(Nc2ncnc(Nc3ccc(cc3)C(=O)N3CCCCC3)n2)c1
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InChI
InChI=1S/C24H25N7O2/c1-2-21(32)27-19-7-6-8-20(15-19)29-24-26-16-25-23(30-24)28-18-11-9-17(10-12-18)22(33)31-13-4-3-5-14-31/h2,6-12,15-16H,1,3-5,13-14H2,(H,27,32)(H2,25,26,28,29,30)
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InChIKey
PIDFACDPHSZEFT-UHFFFAOYSA-N
Physicochemical Property
logP
4.1094
Rotatable Bonds
7
Heavy Atom Count
33
Polar Areas
112.14
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
7
Complexity
33

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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ChEMBL ID
CHEMBL4791249
Table of Molecular Bioactivities Related to the Compound
Cell Viability or Cytotoxicity Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000003 Ramos Homo sapiens (Human)  1
1
IC50 = 6140 nM
   TI
   LI
   LO
   TS
CL000174 Raji Homo sapiens (Human)  1
1
IC50 = 5140 nM
   TI
   LI
   LO
   TS